私人和井口饮用水是抗菌素耐药细菌的储存库
Marwa Alawi1,2, Cian Smyth3, David Drissner4
1Department of Biology, Maynooth University, Maynooth, County Kildare, Ireland. marwa.alawi@mu.ie.
npj antimicrobials and resistance
|January 22, 2025
概括
爱尔兰私人饮用水充当了抗微生物耐药细菌 (ARB) 的储存库. 这项研究强调了需要饮用水监测来跟踪ARB和保护人类健康在一个健康的方法.
科学领域:
- 环境微生物学环境微生物学
- 公共卫生 公共卫生
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 目前的水质测试往往忽略了抗菌素耐药性 (AMR),而是专注于像大肠杆菌这样的指标.
- 关于欧洲饮用水,特别是私人供应中的抗菌素耐药性的数据有限.
- 爱尔兰的家庭饮用水来源于管道,私人井或供水系统.
研究的目的:
- 调查爱尔兰的私人饮用水供应作为抗菌素耐药细菌 (ARB) 的潜在储库.
- 为了识别特定的ARB并描述这些水源中存在的移动抗菌素耐药性 (AMR) 元素.
- 为了强调饮用水监测在One Health监测AMR框架中的重要性.
主要方法:
- 利用公民科学收集爱尔兰各地的私人饮用水样本.
- 从水样中分离并鉴定出格拉姆阴性和格拉姆阳性细菌.
- 描述了抗菌素耐药性概况,并确定了塑体上的移动AMR基因.
主要成果:
- 确定私人饮用水供应作为ARB的储存库,包括机会性病原体,如Enterobacter cloacae和Acinetobacter baumannii.
- 在各种细菌物种中检测到多种药物耐药性,包括Enterococcus物种和E. coli.
- 在三个水样中,在IncF,IncQ和Col-like等质体上发现了耐线索利德的Enterococcus和移动AMR基因.
结论:
- 私人饮用水源是AMR病原体的潜在水槽和来源.
- 饮用水监测对于了解ARB和抗菌素耐药性基因 (ARG) 的移动和持久性至关重要.
- 在饮用水中监测AMR有助于"一健康"的方法,将环境和人类健康联系起来.
更多相关视频
06:54Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
Published on: July 19, 2024
950
05:46Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation
Published on: August 1, 2018
13.0K
相关概念视频
Surface Membrane Barriers
1.0K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.0K
Antibiotic Selection
52.2K
Overview
52.2K
Antimicrobial Proteins
884
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
884
Defense Mechanism Against Infection
6.3K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
6.3K
Defense Against Bacterial Pathogens
1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K
