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肝脏中PD-1表达的增加与PD-1-抗体诱导的肝毒性有关

Miro Saarela1, Essi Parviainen1,2, Ana Lleo3,4

  • 1Department of Oncology and Hematology, Oulu University Hospital, Oulu, Finland.

BMC immunology
|January 23, 2025
PubMed
概括

从检查点抑制剂中消失的胆管综合征 (VBDS) 涉及肝脏免疫细胞的增加,而不是直接的药物毒性. 这种免疫反应不同于其他肝脏疾病,如NASH和PBC.

关键词:
不良事件是不良事件.检查点抑制剂检查点抑制剂淋巴细胞透透.

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