延迟食破坏了被囚禁的新热带蝙蝠的肠道微生物群中的日间振荡
Dominik W Melville1, Magdalena Meyer1, Corbinian Kümmerle1
1Institute of Evolutionary Ecology and Conservation Genomics, Ulm University, 89081 Ulm, Germany.
FEMS microbiology ecology
|January 23, 2025
概括
食时间表显著影响蝙蝠的白天肠道微生物节奏. 破坏养时间改变了微生物的多样性和组成,这表明肠道细菌进化以与宿主养模式保持一致,以实现最佳的营养代谢.
科学领域:
- 微生物生态学 微生物生态学
- 动物生理学 动物生理学
- 时间生物学 时间生物学
背景情况:
- 肠道微生物群中的日间节律是已知的,但人们对其了解甚少.
- 食时间表和肠道环境对这些节律的影响在很大程度上仍未被探索.
研究的目的:
- 研究食时间表对较小长鼻蝙蝠的日常肠道微生物节律的影响.
- 为了区分养线索与肠道pH对微生物振荡的影响.
主要方法:
- 试验性操纵被囚禁的较小长鼻蝙蝠的食时间表.
- 每隔2小时测量便微生物群和肠道pH值.
- 分析微生物多样性 (α和β) 和组成,以及pH值波动.
主要成果:
- 对照蝙蝠在微生物多样性和肠道pH方面表现出强烈的昼间节奏.
- 延迟养会破坏微生物的多样性和组成,但不会破坏肠道pH节奏.
- 特定的细菌系,如Streptococcus,显示了与pH值和养线索相关的改变振荡.
结论:
- 肠道微生物的日常节律受到食时间表的强烈影响.
- 微生物的增殖似乎与宿主食时间同步,以优化代谢支持.
- 这些发现突显了肠道微生物群和宿主昼夜表型的共同进化.
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