状细胞病患者的红细胞利用率:加拿大单一中心的经验
Kelsey Uminski1, Iris Perelman2, Johnathan Mack2,3
1Division of Hematology and Hematological Malignancies, University of Calgary, Calgary, Alberta, Canada.
Transfusion
|January 23, 2025
概括
状细胞病患者经常接受O阴性红细胞,大量用于红细胞交换. 这些数据为改善红细胞使用和管理提供了基线.
科学领域:
- 血液学 血液学 血液学
- 输血医学 输血医学
- 状细胞疾病管理管理
背景情况:
- 在加拿大状细胞病 (SCD) 患者中,红血细胞 (RBC) 的利用率尚未得到很好的定义.
- 这项研究检查了加拿大单一中心SCD队列中的RBC使用情况.
研究的目的:
- 描述和分析SCD成人患者的红细胞利用模式.
- 建立用于RBC使用的基线,以告知未来的质量改进计划.
主要方法:
- 太华医院成年SCD患者的回顾性分析 (2006年1月 - 2019年5月).
- 从医院数据库收集有关医院接触和红细胞输血的数据.
- 后续行动延长至2021年12月.
主要成果:
- 273名患者经历了23,127次住院治疗;165名患者获得了22,538个红血细胞单位.
- 86.5%的红细胞单位是门诊输血;O-阴性单位占输血的29.1%.
- 红细胞交换 (RCE) 在2702次会议中涉及90.2%的输血红细胞单位 (20,333个单位).
结论:
- 该中心的SCD患者经常接受O-负的红细胞单位.
- 在RCE程序中使用了大量的RBC.
- 这些发现为RBC在SCD护理中的管理和优化工作提供了基线.
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