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Updated: May 31, 2025

CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis
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通过miRNA感应导向RNAs对CRISPR活性进行组织特异调节

Antonio Garcia-Guerra1,2,3,4, Chaitra Sathyaprakash5, Olivier G de Jong6

  • 1Department of Physics, University of Oxford, OX1 3PU Oxford, United Kingdom.

Nucleic acids research
|January 23, 2025
PubMed
概括

我们开发了CRISPR MiRAGE,一种用于miRNA激活基因组编辑的新型RNA纳米设备. 这项技术可实现精确的,细胞特异的基因编辑,克服了针对疾病开发有针对性的CRISPR疗法的关键挑战.

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