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通过使用中央复合设计开发和优化固体脂质纳米颗粒来提高BCSII类药物的溶解性 - - 伊特拉科纳

Irfan A Mohammed1, Sriramakamal Jonnalagadda1

  • 1Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Saint Joseph University, Philadelphia, PA.

Pharmaceutical nanotechnology
|January 23, 2025
PubMed
概括

这项研究开发了含伊特拉科纳的固体脂质纳米颗粒 (ICZ-SLNs),以提高口服生物可用性,并为治疗真菌感染创建延长释放特征. 优化的ICZ-SLNs表现出更好的物理化学性能和稳定性.

关键词:
这种药物是伊特拉可纳.中心复合设计.溶解化是冷凍化的一種.固体脂质纳米粒子 固体脂质纳米粒子

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