在水凝间隔器放置时,直肠壁透的危险因素:活检方法的影响
Kohei Hirose1, Yasukazu Nakanishi1, Ryo Andy Ogasawara1
1Department of Urology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
概括
通过直肠活检 (TRB) 在进行前列腺癌放射治疗后显著增加了直肠壁透 (RWI) 的风险. 更小的前列腺大小也会增加这种风险,强调仔细规划.
科学领域:
- 在瘤学瘤学.
- 辐射瘤学 辐射瘤学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 水凝间隔器在前列腺癌放射治疗中用于减少直肠剂量.
- 了解与直肠壁透 (RWI) 相关的因素对于患者的安全至关重要.
研究的目的:
- 为了调查前列腺活检类型和水凝间隔器放置后RWI发生之间的关联.
- 在接受用水凝间隔器进行前列腺癌放射治疗的患者中确定RWI的危险因素.
主要方法:
- 对175名接受水凝间隔器安置的患者进行了回顾性研究.
- 基于跨膜活检 (TPB) 或跨直肠活检 (TRB) 的患者分类.
- 后勤回归分析以确定与RWI相关的因素.
主要成果:
- RWI发生在25.1%的患者中.
- 通过直肠活检 (TRB) 显示RWI发生率明显高 (等级≥2) 与通过膜活检 (TPB) 相比 (23.3%对4.3%,p<0.001).
- TRB (OR=5.81) 和更小的前列腺体积 (≤18.0毫升) (OR=4.23) 是RWI等级≥2.2的显著风险因素.
结论:
- 过直肠活检是水凝间隔器放置后直肠壁透的重要危险因素.
- 更小的前列腺体积也与增加RWI风险有关.
- 活检技术和前列腺大小是规划水凝间隔器放置的重要考虑因素.
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