主导眼睛和对侧眼睛的不对称眼内压力变化:暗室易引起挑测试
Junwei Wang1, Jun Wang2, Tsz Kin Ng1,3
1Joint Shantou International Eye Center, Shantou University, The Chinese University of Hong Kong, Shantou, China.
Seminars in ophthalmology
|January 23, 2025
概括
在前腔室浅的个体中,在暗室易引起的挑性测试 (DRPPT) 后,主导眼睛显示出更大的眼内压力 (IOP) 改变. 这表明主导眼睛中瞳孔堵塞的风险更高,这可能解释了急性视角闭合发作.
科学领域:
- 眼科医生 眼科 眼科
- 之前的细分市场研究
- 眼内压力动态 眼内压力动态
背景情况:
- 浅的前腔是临近角格劳科马的危险因素.
- 暗室易引起的挑测试 (DRPPT) 用于评估角度关闭的风险.
- 了解眼睛对挑性测试的特定反应对于风险分层至关重要.
研究的目的:
- 在DRPPT后评估主导和对侧眼的眼内压力 (IOP) 变化.
- 在DRPPT后,在前腔室浅的受试者中,比较主眼和对侧眼之间的瞳孔反应.
主要方法:
- 一项前性非随机对照试验,涉及43名前腔室浅的受试者.
- 眼内压力 (IOP) 和瞳孔参数在一小时的DRPPT之前和之后被测量.
- 使用卡孔方法进行主导眼睛识别.
主要成果:
- 在DRPPT后,在两只眼睛中都观察到显著的IOP增加 (p < .01).
- 主导眼睛与对侧眼相比,表现出更大的IOP变化 (p < .05).
- 与对侧眼相比,主导眼睛的瞳孔收缩幅度和速度减少 (p < .05).
结论:
- 在DRPPT后,在前腔室浅的个体中,主导眼睛经历了更显著的IOP波动.
- 主导眼睛的瞳孔反应减弱表明瞳孔阻塞的可能性增加.
- 这种不对称性可能有助于急性闭角玻璃眼的单眼呈现.
相关概念视频
Open Angle Glaucoma: Treatment
389
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
389
Glaucoma: Overview
497
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
497
Angle Closure Glaucoma: Treatment
433
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
433


