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Updated: May 31, 2025

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
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利用人类诱导的多能干细胞,功能测试和神经发育障碍机器学习的潜力

Ziqin Yang1,2, Nicole A Teaney1,2, Elizabeth D Buttermore1,2,3

  • 1Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.

Frontiers in neuroscience
|January 23, 2025
PubMed
概括

人类诱导的多能干细胞 (hiPSC) 为研究神经发育障碍 (NDD) 提供了更好的途径. 将hiPSC模型与功能测试和机器学习相结合,可以加速NDD研究和药物发现.

关键词:
在MEA中,MEA是MEA.的成像成像技术可以帮助我们.这是 hiPSC.机器学习是机器学习.神经发育障碍 神经发育障碍补丁紧 补丁紧 补丁紧翻译研究是翻译研究.电压成像 电压成像

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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
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