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功能衰竭中的症状集群:系统性审查
Jaime Gomariz-Ruiz1, David Pérez-Cruzado2,3, Daniel Gutiérrez-Sánchez3,4
1Faculty of Health Sciences, University of Málaga, 29071, Málaga, Spain.
Heliyon
|January 23, 2025
概括
这一系统性审查确定了功能衰竭的常见症状集群,包括胃肠道,神经肌肉和疲劳相关问题. 了解这些集群可以个性化治疗,并减少慢性病患者的副作用.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 内部医学 内部医学
- 临床研究 临床研究
背景情况:
- 慢性病 (CKD) 是一个全球性的健康问题,其特点是功能下降和相关症状.
- 更好地了解CKD症状可以实现个性化的治疗策略.
研究的目的:
- 系统地审查和描述功能衰竭的症状集群.
- 根据发病和患者报告的残疾来对这些症状集群进行分类.
主要方法:
- 按照PRISMA标准进行系统审查.
- 在WOS,Embase,PubMed (2022年11月-2023年1月) 和灰色文献 (2023年5月) 中进行的搜索.
- 包括对患有功能衰竭症状集群的成年人群的横截面研究;使用STROBE检查清单评估质量.
主要成果:
- 在46篇评估文章中,有8篇文章符合纳入标准.
- 确定了常见的症状集群:胃肠道 (恶心,吐),神经肌肉 (疲劳,虚弱),性功能障碍,皮肤问题 (,干燥),厌食症,呼吸障碍和心脏疼痛.
- 数据组织成表格,详细说明参与者资料和症状集群提取方法.
结论:
- 衰竭的症状集群包括胃肠道,神经肌肉,性,皮肤和心脏问题.
- 基于症状集群的治疗提供了比孤立症状管理更大的患者益处.
- 识别症状集群对于开发有针对性的干预措施,简化治疗和最大限度地减少副作用具有临床意义.
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