疾病周期性对生活质量损害的影响-混合方法解释性研究
Ying Shan Cheung1, Winston Tham Zhi Wen2, Ashvin R Chundayil3
1Division of Dermatology, Department of Medicine, National University Healthcare System, Singapore.
JAAD international
|January 23, 2025
概括
疾病周期性通过引起不可预测的症状波动,显著影响生活质量 (QoL). 了解这些机制有助于管理慢性炎症疾病患者的挑战.
科学领域:
- 用于慢性疾病管理的定性研究方法.
- 患者报告的炎症状况的结果.
背景情况:
- 疾病周期性,以不可预测的症状波动为标志,是生活质量 (QoL) 损害的重要预测因素.
- 慢性炎症性疾病如湿疹,牛皮和炎症性关节炎往往表现出循环模式.
研究的目的:
- 调查疾病循环影响患者QOL的潜在机制.
- 开发一个理论框架,以了解患者对周期性疾病活动的体验.
主要方法:
- 对23名患有慢性炎症疾病的成年人进行了1:1半结构面试.
- 采用定性分析,使用基础理论来确定共同的主题.
- 从确定的主题中得出一个理论框架.
主要成果:
- 循环性,定义为不可预测性,不可控制性和可变性,导致生产率变化和日常运作不一致.
- 外部期望与能力波动不一致,加剧了患者的挑战.
- 受内部和外部因素影响的应对能力缓和了周期性对 QoL 的影响.
结论:
- 疾病循环是许多炎症状况的核心特征,影响日常生活和生活质量.
- 该研究提供了一个新的理论框架,以了解和管理周期性疾病患者所面临的挑战.
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