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手术前的肺功能与左心室辅助器件的结果有关

Austin Kluis¹, Aasim Afzal¹, Greg Milligan¹

¹Baylor Scott and White, The Heart Hospital, 4708 Alliance Blvd, Suite 540, Plano, TX, United States.

Surgery in practice and science

|January 23, 2025

概括

手术前的肺功能显著影响左心室辅助装置 (LVAD) 植入后的结果. 较低FEV1和较高FiO2表示的肺功能差,与生存率降低和增加通风和气管切除的需要有关.

科学领域:

心脏病学心脏病学
肺部病理学肺部病理学
医疗器械医疗器械

背景情况:

左心室辅助装置 (LVAD) 植入改善了末期心力衰竭的生存率.
手术前肺功能对短期LVAD结果的影响尚不清楚.

研究的目的:

研究术前肺功能与LVAD植入后的短期结果之间的关联.
确定肺功能指标是否可以帮助LVAD患者的风险分层.

主要方法:

从2017-2022年对107个初级LVAD植入物的回顾性审查.
评估手术前的肺功能测量,包括吸入氧的分数 (FiO2) 和1秒内强制呼气体积 (FEV1).
用于估计生存时间的卡普兰-梅尔方法.

主要成果:

较低的手术前FEV1和较高的手术前FiO2与1年生存率的降低有关.
肺功能状态与术后呼吸器时间和气管切除术的发生率相关.
整体1年生存率为86.8%,中位数的术后呼吸器时间为20.4小时.

结论:

手术前的肺功能是短期LVAD结果的重要预测因素.
对肺功能的评估对于LVAD候选人的术前风险分层至关重要.
优化肺部评估可能会改善LVAD接受者的患者选择和术后管理.

关键词:

最终阶段的心力衰竭.左心室辅助装置的使用肺功能测试试验肺功能测试试验风险分层是指风险的分层.

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