在受试者中没有创伤性脑损伤的痴呆和中,中年女性:基于人口的病例控制研究
Shu-Fen Chu1, Cheng-Hua Ni2,3,4, Kuo-Hsing Liao5,6,7,8
1College of Nursing and Health Management, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Journal of Alzheimer's disease : JAD
|January 23, 2025
概括
与更高的痴呆风险有关,即使没有创伤性脑损伤 (TBI) 的病史. 这种关联在55-64岁的女性中尤为明显.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 老年病的医生 老年病的医生
背景情况:
- 创伤性脑损伤 (TBI) 是痴呆症的一个已知的危险因素.
- 在没有TBI病史的人群中,痴呆和之间的联系存在有限的研究.
研究的目的:
- 在没有TBI病史的基于人口的队列中调查痴呆和之间的关系.
- 为了确定特定的人口群体在更高的风险.
主要方法:
- 一项基于人群的研究包括30715名没有TBI病史的患者.
- 6,143名患者的队列与24,572名没有的患者进行了比较.
- 分层考克斯比例危险回归分析了痴呆症风险.
主要成果:
- 患有的患者 (没有TBI病史) 患痴呆的风险增加了84% (aHR=1.84).
- 与男性相比,55-64岁的女性患的痴呆风险是男性的4.5倍.
- 75岁以上患者的痴呆风险 (aHR=1.45) 比其他年龄组低.
结论:
- 与痴呆的风险增加有关,独立于TBI.
- 的预防和管理策略应优先考虑55-64岁的女性.
- 需要进一步的研究来了解这种关联背后的机制.
更多相关视频
09:16Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
Published on: June 21, 2019
25.5K
12:09Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
Published on: August 5, 2014
18.0K
相关概念视频
Arteries of the Lower Limbs
177
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
177
Dementia
93
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
93
Seizures: Classification
300
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
300
