在接受软组织手术的未服用阿片类药物的患者中,同时使用二和阿片类药物
Thompson Zhuang1, Ellis M Berns1, Hannah H Lee1,2
1University of Pennsylvania, Philadelphia, USA.
概括
手术前使用类药物的患者接受了更多的阿片类药物,并且长期使用阿片类药物的几率更高. 考虑为这些患者提供非阿片类药物止痛药.
科学领域:
- 整形外科手术 整形外科手术
- 疼痛管理 疼痛管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 同时使用阿片类药物和二甲类药物会增加镇静和过量使用的风险.
- 在手术患者使用二胺类药物的手术期间的阿片类药物处方模式尚不清楚.
研究的目的:
- 在未服用阿片类药物手术的手术患者中调查外科期间的阿片类药物利用,同时使用二.
- 评估手术前使用二胺与阿片类药物处方,新持续使用阿片类药物和术后结果之间的关联.
主要方法:
- 对成年手术患者的行政索赔数据库 (2011-2021) 的分析.
- 在手术前90天内识别曾经服用过阿片类药物的患者,并处方二.
- 多变量回归模型根据人口和临床因素进行调整,以评估结果,包括阿片类药物处方,新的持续阿片类药物使用,ED访问和手术.
主要成果:
- 服用类药物的患者在经过调整后,接受外科手术期间的阿片类药物处方的几率显著更高,并且服用的阿片类药物量更高.
- 与非使用者相比,使用二二的患者患上新的,持续的阿片类药物使用的几率增加了1.48倍.
- 术前使用二二类药物与术后急诊室访问量增加和手术利用率增加有关.
结论:
- 使用类药物手术的阿片类药物原始手术患者更频繁地和更高量的阿片类药物被处方.
- 这些患者面临着发展新的,持续的阿片类药物使用的可能性增加.
- 外科医生应该考虑减少对服用类药物的患者的阿片类药物处方,优先考虑非阿片类药物疼痛管理策略.
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