牙科抗生素处方趋势:使用日本国家数据库进行描述性研究
Kaho Hirayama1, Naoki Kanda1, Hideki Hashimoto1,2
1Division of General Medicine, Jichi Medical University, Tochigi, Japan.
Journal of public health dentistry
|January 23, 2025
概括
日本牙科的抗生素处方略有下降,但第三代类仍然占主导地位. 加强抗微生物药物管理至关重要,尤其是在牙科诊所.
科学领域:
- 牙科公共卫生 牙科公共卫生
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 日本牙医的抗生素处方模式并未得到充分理解.
- 2016年实施了一项国家抗微生物药物管理计划.
研究的目的:
- 描述2015财年至2020财年日本牙科抗生素处方趋势.
- 评估国家抗微生物药物管理计划的影响.
主要方法:
- 日本国家行政索赔数据库 (2015-2020财年) 的横截面分析.
- 每年1000名居民处方费率的计算,以2015财年人口为标准.
- 普森回归分析用于评估处方率的变化.
主要成果:
- 从2015财年到2020财年,总体抗生素处方减少了6%.
- 第三代头素在2020财年占牙科处方的52.3%.
- 青素的使用在医院显著增加,但在诊所的使用较少,第三代黄仍然普遍存在.
结论:
- 第三代头素仍然是牙科中最常被处方的抗生素.
- 抗菌药物管理工作需要加强,特别是在牙科诊所内.
- 观察到医院和诊所之间的抗生素处方轮班的差异.
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