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Updated: May 31, 2025

Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
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在一个具有挑战性的双特异性抗体染色学步骤的in silico优化

Zsófia Bencze1, Tobias Hahn2, Henri Kornmann1

  • 1Biologics Process Development, Ferring Biologics Innovation Center, Epalinges, Switzerland.

Biotechnology progress
|January 23, 2025
PubMed
概括

本研究介绍了用于离子交换色谱的体颗粒吸附 (CPA) 建模工作流程. 该模型有效优化双特异抗体净化,实现高产量和纯度,同时识别关键过程参数.

关键词:
两种特异性抗体分离的分离.体颗粒吸附异热法是体颗粒吸附异热法.离子交换色谱学 离子交换色谱学机械模型模型机械模型过程改进 过程改进过程稳定性测试 过程稳定性测试

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