根据DOHaD概念,每一个民族的低出生体重定义都应该相同吗?
Yoshifumi Kasuga1, Mamoru Tanaka1
1Department of Obstetrics and Gynecology, Keio University School of Medicine, 5 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Pediatric reports
|January 23, 2025
概括
低出生体重 (LBW) 影响长期健康,但定义因国家而异. 这项研究表明,对于个性化的医疗保健和跨种族更好的风险预测,需要一个普遍的LBW定义.
科学领域:
- 围产期健康 围产期健康
- 公共卫生 公共卫生
- 人类测量学 人类测量学.
背景情况:
- 低出生体重 (LBW) 与当前和未来的健康问题有关.
- 目前的LBW定义是普遍的,不考虑种族和国家差异.
- 母亲身高与LBW发病率有负相关性.
研究的目的:
- 探索一个单一的LBW定义在不同的人口中的含义.
- 调查现有增长图表对不同种族的适用性.
- 倡导一个标准化的,独立于种族的LBW定义.
主要方法:
- 来自多个国家的国家出生体重数据的汇编.
- 对出生体重图表进行比较分析,包括INTERGROWTH-21st和日本特定图表.
- 关于不同LBW截止值及其对围产期结果评估的影响的文献综述.
主要成果:
- 发现母亲的身高与LBW发生率有负相关性.
- 国际增长21世纪图表可能不能准确地代表日本人口.
- 在全球用于围产期风险评估的LBW截止值中存在差异.
结论:
- 目前还没有一个独立于母亲原籍国的普遍LBW定义.
- 制定一个标准化,包括种族在内的LBW定义对于个性化医疗保健至关重要.
- 需要进行进一步的研究,以确定各种种族群体的适当LBW截止值.
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