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Updated: May 31, 2025

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微塑料和纳米颗粒通过皮肤透:尺寸,形状和表面化学的影响

Arianna Menichetti1,2, Dario Mordini1, Marco Montalti1,2

  • 1Department of Chemistry "Giacomo Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy.

Journal of xenobiotics
|January 23, 2025
PubMed
概括

微粒和纳米粒子可以穿透皮肤,作为药物的输送载体或毒素的载体. 颗粒的特性,如大小和形状,影响了受控的输送和不需要的毒素运输.

关键词:
药物输送是药物输送的过程.微塑料微塑料的使用纳米颗粒是一种纳米粒子.纳米塑料是一种纳米塑料.毒性的毒性 毒性的毒性

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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