在长期护理设施中通过药剂师调解的降低处方:系统审查
João Rafael Gonçalves1, Neuza Magalhães2, Sara Machado1
1iMed.ULisboa-Research Institute for Medicines, Faculty of Pharmacy, University of Lisbon, 1649-003 Lisboa, Portugal.
Pharmacy (Basel, Switzerland)
|January 23, 2025
概括
在长期护理 (LTC) 中,药剂师主导的降低处方是可行的,减少了药物数量. 然而,研究质量各不相同,患者拒绝是优化老年人药物使用的障碍.
科学领域:
- 老年学是一门学科.
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在长期护理 (LTC) 居民中,多病症和多药性是常见的,增加了与药物有关的问题.
- 在LTC中,老年人特别容易受到药物不良反应的影响,因此需要像抑郁症这样的干预措施.
- 药剂师在管理医疗保健机构内的药物和临床活动中发挥着至关重要的作用,包括LTC.
研究的目的:
- 系统地识别和评估长期护理机构中药师介导的抑郁治疗干预措施.
- 评估药剂师主导的药物评价和LTC中的减处方的有效性和可行性.
主要方法:
- 使用PubMed,Scopus和知识网络进行了遵循PRISMA指南的系统审查.
- 搜索策略结合了专业,护理类型和设置领域的18个关键字.
- 十五项研究进行了质量评估,涉及6928名患者和45名药剂师,符合纳入标准.
主要成果:
- 分析了药剂师介导的特异性和非特异性抑郁症.
- 常见的向药物组包括ATC A,C,M,N和抗胆固醇药.
- 建议的接受率有所不同 (30-100%),药物数量有所下降,但跌倒和生活质量的结果是混合的. 观察到节省了成本.
- 患者/家人的拒绝是抑郁症的关键障碍.
结论:
- 在长期护理环境中,药剂师介导的抑郁处方是一种可行的策略.
- 研究中的方法异质性限制了可靠的结论和比较.
- 针对特定的药物群体和了解障碍/助力因素对于优化LTC中减缓处方干预至关重要.
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