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与宿主CD73的删除相关的自身免疫性降低

Beanna Okeugo1, Shabba A Armbrister1, Rhea C Daniel1

  • 1Department of Pediatrics, Division of Gastroenterology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.

ImmunoHorizons
|January 23, 2025
PubMed
概括

移除CD73意外减少了皮小鼠的自身免疫严重性,表明CD73向可能治疗免疫缺陷中的T细胞介导性皮肤炎.

关键词:
艾佩克斯综合征 (IPEX综合征) 是一种症状.皮肤炎是一种皮肤炎.原发性免疫缺陷 - 一次性免疫缺陷监管性T细胞监管性T细胞皮皮的 皮的甲状腺细胞 (thymocytes) 是一种细胞.

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