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两年随机对照试验环形与细分腹外角外科手术在患有初级开角玻璃眼患者
Ahmed Samy Elwehidy1, Nader Hussein Lotfy Bayoumi2, Mostafa A S Elwehidy3
1Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Japanese journal of ophthalmology
|January 23, 2025
概括
在初级开角玻璃眼病 (POAG) 患者中,粘周周接-眼切除术 (VCST) 与细分粘周切除术 (VT) 相比,可以提供更优异的眼内压力降低. 这种角度手术提供了持续的IOP控制至少两年.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 外科手术的结果
背景情况:
- 主要开角青光眼 (POAG) 是不可逆转失明的主要原因.
- 有效的手术管理对于降低眼内压力 (IOP) 和预防视神经损伤至关重要.
- 基于角度的玻璃眼外科手术正在因其有效性和安全性而获得吸引力.
研究的目的:
- 为了比较粘性环形接轨膜切除术 (VCST) 和刚性探针细分粘性轨膜切除术 (VT) 的外科结果.
- 评估这些双角度手术技术在POAG患者的疗效和安全性.
主要方法:
- 一项前性随机受控研究,涉及107名POAG患者的166只眼睛.
- 患者被随机分配,接受VCST或VT.
- 随访时间延长至24个月,成功率定义为IOP≤18 mmHg,与基线相比降低40%.
主要成果:
- 与基线相比,VCST和VT都显著降低了IOP.
- 与VT组 (15.5±0.9 mmHg) (p<0.001) 相比,VCST组实现了较低的最终IOP (12.4±1.2 mmHg),与VT组相比 (15.5±0.9 mmHg) (p<0.001).
- 与VT (79.8%) 相比,VCST在24个月后的成功率 (85.4%) 较高,并且需要更少的随后的玻璃眼手术.
结论:
- 细分和周边角手术都有效降低POAG的IOP至少两年.
- 圆角外科手术 (VCST) 提供了更大的IOP减轻和需要更少的后续干预.
- 这些发现支持VCST作为潜在的更有效的选择来管理POAG.
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