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Updated: May 31, 2025

Observing Mitotic Division and Dynamics in a Live Zebrafish Embryo
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对凝聚素的ANKRD11结合表明KBG综合征和康奈莉亚·德朗格综合征之间存在联系

Haiyang Liu1,2, Hao Li3,4, Qixu Cai5

  • 1Shenzhen Key Laboratory of Biomolecular Assembling and Regulation, Department of Neuroscience, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.

Proceedings of the National Academy of Sciences of the United States of America
|January 23, 2025
PubMed
概括

ANKRD11蛋白质突变通过破坏其与凝聚素复合物的相互作用,导致发育异常,导致KBG综合征和自闭症谱系障碍. 这项研究揭示了将ANKRD11,凝聚素和这些疾病联系在一起的分子机制.

关键词:
在 ANKRD1111 里面.康奈莉亚·德朗格综合征 (Cornelia de Lange综合征) 是一种对于KBG综合征来说,这是一个很好的例子.凝聚力 在凝聚力中

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