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Updated: May 31, 2025

Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota
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Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota

Published on: May 23, 2025

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人类对葡萄糖-6-酸盐的识别和水解的结构洞察力 G6PC1

Zhanyi Xia1,2, Chuanyu Liu1,2, Di Wu1,2

  • 1Beijing National Laboratory for Condensed Matter Physics, Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China.

Proceedings of the National Academy of Sciences of the United States of America
|January 23, 2025
PubMed
概括

我们确定了人类葡萄糖-6-酸酶 (G6Pase) 的结构,揭示了它如何结合葡萄糖-6-酸盐 (G6P) 来调节血糖. 这为糖尿病和GSD-1a.提供了洞察力.

关键词:
在G6P的水解中.在 G6PC1 里面.G6 阶段 阶段这就是GSD-1a.化-EM结构的结构.

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