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Updated: May 31, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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在癌症中与酶融合,突变和副本数量改变的可操作变化的比较

Shinsuke Suzuki1,2,3, Toshiaki Akahane1,4, Akihide Tanimoto4

  • 1Cancer Center, Kagoshima University Hospital, Kagoshima, Japan.

PloS one
|January 23, 2025
PubMed
概括

激酶融合是癌症的关键驱动因素,但这些变化的患者的可操作目标比突变或副本数量变化的患者少. 检测激酶变化对于开发向疗法至关重要.

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