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Updated: May 31, 2025

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肺动脉高血压中的溶酶体功能障碍和炎症性固醇代谢

Lloyd D Harvey1,2,3, Mona Alotaibi4,5,6, Yi-Yin Tai2,3

  • 1Medical Scientist Training Program, University of Pittsburgh, Pittsburgh, PA, USA.

Science (New York, N.Y.)
|January 23, 2025
PubMed
概括

核受体联合激活剂7 (NCOA7) 缺乏导致血管炎症,并恶化肺动脉高血压 (PAH). 恢复NCOA7功能可以逆转PAH,揭示新的治疗点.

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