糖尿病和耳之间的关联:一个元分析
Shi Luo1, Jianxue Wen1, Qilong Bao1
1Department of Otorhinolaryngology and Head and Neck Surgery, The Affiliated Zhuzhou Hospital Xiangya Medical College CSU, Zhuzhou, China.
Biomolecules & biomedicine
|January 23, 2025
概括
糖尿病 (DM) 与较高的耳风险有关. 这项对200多万参与者的元分析证实了显著的关联,强调了糖尿病患者耳监测的必要性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 流行病学 流行病学
背景情况:
- 糖尿病 (DM) 是一种潜在的,但尚未证实的,耳风险因素.
- 关于DM-耳关联的现有证据需要进行系统的评估.
研究的目的:
- 进行一项元分析,评估DM与耳之间的关联.
- 综合观察性研究的数据以确定风险.
主要方法:
- 在PubMed,Embase和Web of Science的系统文献搜索.
- 包括12项观察性研究,参与者超过220万.
- 使用随机效应模型进行聚合分析;通过NOS进行质量评估;偏差评估.
主要成果:
- 在DM和耳之间发现了显著的关联 (OR:1.18,95%CI:1.06-1.31,P = 0.002).
- 观察到中等异质性 (I2=51%);敏感性分析证实了强度.
- 在子组分析中没有发现显著差异;没有检测到出版偏差.
结论:
- 脑膜炎与 tinnitus 的风险增加有显著的关联.
- 需要进一步的研究来阐明潜在的机制和因果关系.
- 强调监测糖尿病患者的耳的重要性.
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