在美国人口中暴露于per-和多基物质 (PFAS):NHANES 1999 - 2020年3月
Julianne Cook Botelho1, Kayoko Kato1, Lee-Yang Wong1
1Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Environmental research
|January 23, 2025
概括
尽管水平下降,但超过96%的年轻美国人血液中仍有可检测的"永久化学物质" (PFAS). 像PFHpS一样,新的PFAS也很普遍,凸显了持续暴露的担忧.
科学领域:
- 环境健康科学 环境健康科学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 和多基基物质 (PFAS) 或"永久化学品"是自20世纪40年代以来使用的持续性环境污染物.
- 在美国饮用水中广泛检测到PFAS引起了公众和科学界的重大关注.
- 了解人口层面的暴露趋势对于公共卫生风险评估至关重要.
研究的目的:
- 从1999年至2020年评估四种遗留PFAS (PFHxS,PFOS,PFOA,PFNA) 的血清度的时间趋势.
- 评估2017-2018年两种新测量的PFAS (PFHpS,9CLPF) 的血清度和人口预测指标.
- 为了比较美国普通人口中遗留的PFAS配置文件与环境暴露社区的PFAS配置文件.
主要方法:
- 从九个国家健康和营养检查调查 (NHANES) 周期 (≥12年) 的血清PFAS度数据分析.
- 随着时间的推移 (1999-2000年至2017年至2020年3月) 的度变化统计评估.
- 在2017-2018年NHANES数据中评估与PFHpS和9CLPF度相关的人口因素.
主要成果:
- 四个遗留的PFAS的几何平均度从1999-2000年至2017年至2020年3月大幅下降 (16%-87%).
- 尽管下降了,但在2017年至2020年3月期间,超过96%的12-19岁的个人有可测量的遗留PFAS度.
- 在估计的78%的美国人群中发现了可检测的PFHpS度,9CLPF在8% (在亚洲人群中不成比例).
结论:
- 遗留的PFAS在美国人口中仍然可以广泛检测到,即使是在生产变化后出生的年轻人中.
- 新测量的PFAS,如PFHpS,表明持续广泛的暴露.
- 对于监测PFAS暴露趋势,识别来源和评估缓解策略,NHANES数据非常有价值.
关键词:
9 在CLPF.生物监测 生物监测尼汉斯 (NHANES) 是一个名人.在PFAS中,有很多方法.在PFHpS中,在PFHxS中使用.这就是PFNA的PFNA.这就是PFOA的PFOA.这就是为什么PFOS是PFOS.血清的血清是什么意思更多相关视频
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