在前性痴呆症前性静脉狭窄症中Azygos静脉狭窄症 缩大脑综合征
Wouter I Schievink1, Marcel M Maya2, Rola Saouaf2
1From the Department of Neurosurgery (W.I.S., R.B.T.), Cedars-Sinai Medical Center, Los Angeles, California schievinkw@cshs.org.
AJNR. American journal of neuroradiology
|January 23, 2025
概括
脊髓脑脊液 (CSF) 泄漏可能导致模仿前性痴呆症的症状. 通过MRI静脉图识别的阿齐戈斯静脉狭窄,可能导致脑综合征,在一些患者中是可治疗的原因.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 放射学 放射学是一门学科.
背景情况:
- 行为变异性前性痴呆症 (bvFTD) 症状可能来自自发的内低血压和严重的脑.
- 识别脊髓大脑脊髓液 (CSF) 泄漏是具有挑战性的,标准治疗的成功也有限.
- 系统静脉循环异常与CSF泄漏病理学有关.
研究的目的:
- 在患有bvFTD垂脑综合征和反复性症状的患者中调查全身静脉循环.
- 为了确定脑脊液 (CSF) 损失导致大脑松的潜在静脉原因.
主要方法:
- 对21名患有bvFTD松大脑综合征但没有可识别的脊髓中枢液泄漏的患者的回顾性审查.
- 进行了全身静脉循环成像 (MR或CT静脉图).
- 患者报告的结果使用SIH残疾评估得分 (SIHDAS) 进行评估.
主要成果:
- 七名患者 (33%) 呈现静脉狭窄.
- 在3名患者中发现了阿齐戈斯静脉狭窄症,2名患者在支架放置后表现出显著的症状改善.
- 其他静脉 (关静脉,静脉) 或脊髓静脉通路的狭窄并没有产生临床改善.
结论:
- 孤立的阿齐戈斯静脉狭窄是导致脊髓中枢液损失和脑综合征的潜在原因.
- 系统性静脉成像,特别是形系统,应考虑耐火性bvFTD松大脑综合征.
- 在15%的患者中发现了可治疗的静脉病变,这凸显了这种诊断途径的重要性.
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