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对心表脂肪组织和急性冠状动脉综合征之间的相关性分析

Gao Zhihong¹, Zuo Yuqiang¹, Jia Linyi²

¹Health Examination Center, The Second Hospital of Hebei Medical University, Shijiazhuang, 050005, Hebei, People's Republic of China.

Scientific reports

|January 23, 2025

概括

脊心脂肪组织密度 (EATD) 和体积 (EATV) 与急性冠状动脉综合征 (ACS) 有关. EATD是ACS比EATV和传统风险因素更强的预测因素,为心血管疾病风险提供了新的见解.

科学领域:

心脏病学心脏病学
放射学放射学是一门学科.
生物医学工程生物医学工程

背景情况:

副心脏脂肪组织 (EAT) 是代谢活跃的,与心血管疾病有关.
了解EAT体积 (EATV) 和密度 (EATD) 与急性冠状动脉综合征 (ACS) 之间的关系对于风险分层至关重要.

研究的目的:

调查EAT体积 (EATV) 和EAT密度 (EATD) 与急性冠状动脉综合征 (ACS) 的发生之间的相关性.
评估与传统风险因素相比,针对ACS的EATV和EATD的预测价值.

主要方法:

一项涉及355名受试者 (175名ACS,180名非ACS) 的病例控制研究,应用了倾向性得分匹配.
在ACS和非ACS组之间比较临床数据,EATV和EATD.
后勤回归和ROC曲线分析以确定独立预测因素并评估预测能力.

主要成果:

在ACS组中血压升高,EATV,EATD,空腹血糖,甘油三和高灵敏性C反应蛋白.
EATV和BMI之间的中等正相关性;EATD和年龄之间的负相关性较弱.
EATV和EATD都是ACS的独立预测指标,EATD显示出最高的预测值 (AUC = 0.859).

结论:

EAT的体积和密度与急性冠状动脉综合征有显著的关联.
EAT密度是ACS的强有力的独立预测因素,其表现优于EAT体积和传统的风险因素.
EATD可以作为ACS风险评估的有价值的成像生物标志物.

关键词:

急性冠状动脉综合征是什么冠状动脉疾病是一种冠状动脉疾病.胸前脂肪组织的副心脏脂肪组织.影响因素影响因素.

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