美国人中氧化平衡得分和心力衰竭之间的关联:NHANES (2007-2018)
Xiaozhuo Xu1,2, Xueli Wang1,2, Xu Han3
1Department of Geriatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, 210029, China.
BMC cardiovascular disorders
|January 24, 2025
概括
较高的抗氧化剂摄入量,以氧化平衡得分 (OBS) 衡量,与美国成年人心力衰竭 (HF) 的风险较低有关. 采用富含抗氧化剂的饮食和生活方式可能有助于预防心力衰竭.
科学领域:
- 心血管健康 心血管健康
- 营养流行病学 营养流行病学
- 氧化压力研究研究 氧化压力研究
背景情况:
- 氧化平衡得分 (OBS) 和心力衰竭 (HF) 之间的关联仍在争论中.
- 较高的OBS分数表明更大的抗氧化剂暴露,反映了全身氧化应激状态.
研究的目的:
- 调查OBS与美国成年人中HF患病率之间的关系.
- 为了确定增加抗氧化剂摄入量是否与降低HF风险有关.
主要方法:
- 国家健康和营养检查调查 (2007-2018) 的横截面分析.
- 多变量线性回归模型被用来评估45岁及以上的成年人之间的关联.
- 进行了相互作用试验和子组分析.
主要成果:
- 心力衰竭的发病率为3.84%.
- 在OBS和HF之间观察到一个显著的反向关系 (OR:0.96,95%CI:0.95-0.98).
- 在OBS的最高四分位数中,与最低四分位数 (OR:0.55,95%CI:0.41-0.74) 的人相比,OBS的最高四分位数中的人患HF的可能性要低45% (OR:0.55,95%CI:0.41-0.74).
结论:
- 氧化平衡评分 (OBS) 与心力衰竭有着强烈的负面关联.
- 这些发现强调了富含抗氧化剂的饮食和生活方式对于预防心力衰竭的重要性.
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