麻醉对接受白内障手术的成年人术后认知功能障碍的影响:系统性审查
Elaheh Foroughi1, Etrusca Brogi2, Francesco Forfori3
1Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
BMC anesthesiology
|January 24, 2025
概括
这次审查发现,全身麻醉可能会增加白内障手术后术后认知功能障碍 (POCD) 的风险. 某些药物如胺可以减少POCD,但需要更多的研究才能获得确的证据.
科学领域:
- 麻醉学 麻醉学
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 手术后认知功能障碍 (POCD) 是白内障手术后的一个担忧.
- 麻醉方法和药物可能会影响POCD的发生率.
研究的目的:
- 系统地审查麻醉方法和药物影响白内障手术后POCD的证据.
- 在白内障手术患者中调查麻醉和POCD之间的关系.
主要方法:
- 从2000年到2024年发表的9项临床试验 (1014名参与者) 的系统综述.
- 搜索了科学网,PubMed,Scopus;使用JBI检查清单评估文章质量.
- 分析了对POCD发病率进行麻醉方式和药物的比较的研究.
主要成果:
- 在手术后的第1天和第7天,局部和局部麻醉之间的POCD没有显著差异.
- 与局部麻醉相比,全身麻醉的POCD发病率大约是局部麻醉的两倍.
- 与对照组相比,胺,米达佐拉姆或德克斯梅德托米丁可能会降低POCD.
结论:
- 关于麻醉技术和影响POCD的药物的证据是不确定的.
- 需要进一步的研究才能得出最终的结论.
- 麻醉选择应考虑患者的风险因素,特别是对于有认知病史的老年患者.
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