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在软骨再生过程中,由介质细胞流体细胞衍生的细胞外囊泡:潜力和局限性

María Piñeiro-Ramil1,2,3, Iván Gómez-Seoane1, Ana Isabel Rodríguez-Cendal1,2,3

  • 1Grupo de Investigación en Terapia Celular y Medicina Regenerativa, Instituto de Investigación Biomédica de A Coruña (INIBIC), Fundación Pública Gallega de Investigación Biomédica INIBIC, Complexo Hospitalario Universitario de A Coruña (CHUAC), Servizo Galego de Saúde (SERGAS), A Coruña, 15006, Spain.

Stem cell research & therapy
|January 24, 2025
PubMed
概括

介质细胞 stromal 细胞衍生的小细胞外囊泡 (sEVs) 显示通过促进软骨修复和减少炎症来治疗关节炎. 需要进行进一步的研究,以优化其用于软骨再生的临床应用.

关键词:
无细胞疗法是一种无细胞疗法.冠状细胞 (chondrocytes) 是一种细胞.外基因组是外基因组的组成部分.这是一个OAOA.

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Mesenchymal Stem Cells01:19

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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...