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对抗食物过敏的天然生物活性化合物的全面审查,以对抗食物过敏
Lu Liu1, Jing Dai1, Qingli Yang1
1School of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, PR China.
Food research international (Ottawa, Ont.)
|January 24, 2025
概括
自然化合物通过向肠道微生物群和减少过敏反应,为控制食物过敏提供了一个有希望的替代方案. 这项研究审查了自然物质及其机制,以开发有效的抗过敏功能性食品.
科学领域:
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 食物过敏是一个重要的全球健康问题,目前的治疗方法有局限性.
- 对食物过敏的药物可能会引起不良反应并破坏肠道菌群.
- 研究重点是天然成分作为安全有效的抗过敏剂.
研究的目的:
- 提供对反食物过敏研究的全面概述.
- 为了分类具有抗过敏性质的天然物质.
- 检查这些天然生物活性物对肠道微生物群和食物过敏的影响.
主要方法:
- 审查关于食物过敏机制和评估方法的现有文献.
- 已证明具有抗过敏作用的天然物质的分类.
- 对研究自然化合物对肠道微生物群的影响的分析.
主要成果:
- 自然活性物通过多种途径缓解过敏反应,包括Th1/Th2平衡调节和降低IgE合成.
- 这些物质可以防止细胞脱粒和介质释放.
- 用天然生物活性物向肠道微生物群显示出控制食物过敏的潜力.
结论:
- 自然活性剂为管理食物过敏提供了多重目标的方法.
- 肠道微生物群在食物过敏的发展和管理中起着至关重要的作用.
- 使用天然化合物的饮食干预措施为功能性食品开发提供了一个有希望的战略,以缓解食物过敏.
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