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Updated: May 31, 2025

Delivery of Modified mRNA in a Myocardial Infarction Mouse Model
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在由Matrine和Evodiamine诱导的心脏毒性中,一致的RNA表达和RNA修饰模式

Guanhua Fang1,2, Yanming Shen1, Xinyue Gao3

  • 1Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.

Frontiers in pharmacology
|January 24, 2025
PubMed
概括

传统中国医学 (TCM) 可以引起心脏毒性. 这项研究使用生物信息学来发现常见的分子通路,如m6A和A-to-I修饰,涉及TCM诱导的心脏损伤.

关键词:
埃沃胺 (evo) 是一种马特林 (M) 的意思编辑RNA的RNA编辑心脏毒性心脏毒性m6A (N6 - 甲基氨酸) 的使用.

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