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Updated: May 31, 2025

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
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ZBP1感知到Brucella abortus DNA触发I型干扰素信号通路和展开的蛋白质反应激活

Marco Túlio R Gomes1, Erika S Guimarães1,2, Sergio C Oliveira1,3,4

  • 1Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Frontiers in immunology
|January 24, 2025
PubMed
概括

Z-DNA结合蛋白1 (ZBP1) 部分感知Brucella abortus DNA,有助于I型干扰素 (IFN) 的产生和信号传递. ZBP1对控制细菌感染并不重要,但在先天性免疫反应中起作用.

关键词:
布鲁塞拉流产 (Brucella abortus) 是一种流产.在 ZBP1 中,ZBP1 是巨细胞是一个巨细胞.这是一种I型干扰子.苏维埃叛乱发生了什么?

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