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头骨对多层脑组织的光声成像的影响嵌入式血管在不同光源类型下的多层脑组织:建模和模拟

Xi Yang^1,2, Chengpeng Chai^1,2, Yun-Hsuan Chen^1,2

¹CenBRAIN Neurotech Center of Excellence, School of Engineering, Westlake University, Hangzhou 310030, China.

Bioengineering (Basel, Switzerland)

|January 24, 2025

概括

这项研究模拟了通过头骨进行光声成像,揭示了不同的光源如何影响图像质量. 了解这些效应是改善脑成像技术和选择最佳光源的关键.

科学领域:

生物医学成像技术生物医学成像技术
光学物理学光学物理学
声学物理声学物理

背景情况:

光声学成像在人类应用中面临挑战,原因是骨的光学散射和声学减弱.
提高光声信号的生成和传播对于有效的脑成像至关重要.

研究的目的:

探索和增强光声生成和传播通过头骨条件.
研究不同类型的光源对大脑血管系统的光声成像的影响.
在不同的光学和声学条件下评估图像重建特征.

主要方法:

进行了多层大脑模型的光声学模拟,其中嵌入了血管.
在不同的光源类型下分析了光学模拟结果.
进行了声学模拟,并没有头骨条件用于图像重建.
评估了目标血管的图像重建特征,形态和强度变化.

主要成果:

最初的光声信号显示出一致的光源类型对不同位置的信号强度的影响.
与初始信号相比,重建的图像表现出不同的光源类型依赖.
具有和没有头骨条件的特征声信号传输及其对图像重建的影响.

结论:

这项研究提供了对声信号行为及其对通过头骨图像重建的影响的见解.
这些发现为在光声成像中选择合适的光源提供了理论基础.
结果有助于克服人类光声学脑成像方面的挑战.

关键词:

蒙特卡洛模拟的蒙特卡洛模拟声学模拟的声学模拟一个血管,一个血管.脑部成像脑部成像在K-波浪中.通过光学模拟来进行模拟.头骨头骨头头骨头骨头骨头骨头骨

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