牙周炎,牙炎,牙脱落和中风之间的关联:一项总体研究与元分析
Jad El Masri1,2,3,4,5, Ahmad Al Malak6, Diala El Masri4,7
1INSERM U955-E01, Institut Mondor de Recherche Biomédicale (IMRB), Université Paris-Est Créteil, 94010 Créteil, France.
Brain sciences
|January 24, 2025
概括
牙周炎和牙脱落显著增加了脑血管事故 (CVA) 的风险. 然而,牙炎没有显示出与CVA的显著联系. 这凸显了严重牙周病对血管健康的影响.
科学领域:
- 心血管研究研究心血管研究
- 口腔卫生流行病学 口腔卫生流行病学
- 系统性疾病机制 系统性疾病机制
背景情况:
- 脑血管疾病 (CVA) 有可修改和不可修改的风险因素.
- 牙周病 (PD) 与CVA有关,研究表明有直接或间接的相关性.
- 了解牙周健康和CVA之间的关系对于公众健康至关重要.
研究的目的:
- 系统地审查和分析现有的关于牙周病和脑血管疾病之间的关联的元分析.
- 评估牙周炎,牙炎和牙损失的证据作为CVA的风险因素.
- 综合发现,以更好地了解相关的病原性途径.
主要方法:
- 通过使用PubMed,Cochrane,Scopus和Web of Science数据库进行了对元分析的综合审查.
- 搜索是在2024年3月进行的,遵循乔安娜·布里格斯研究所的指导.
- 使用AMSTAR进行质量评估,使用审查经理进行聚合分析.
主要成果:
- 包括七个高质量的元分析.
- 牙周炎显著增加了CVA风险 (OR = 2.32,RR = 1.22).
- 牙损失也显示出与CVA的关联,尽管在较小程度上 (0.78). 牙炎没有显示出显著的关联 (RR = 1.32).
结论:
- 牙周炎和牙脱落是脑血管事故的确诊危险因素.
- 牙炎似乎在心血管病发作中没有显著的作用.
- 牙周病的炎症过程可能会导致动脉样硬化变化的致病,导致CVA.
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