IDH:,

Alexander Bray1, Vaibhav Sahai1

  • 1Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.

PubMed
概括

异酸脱酶 (IDH) 基因的突变通过产生R2HG来驱动胆管癌 (CCA). 针对突变的IDH (mIDH) 使用像ivosidenib这样的药物为CCA患者提供了一个有前途的治疗策略.

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