美国土著人口中心血管疾病风险因素
Krista Goerger1, Karla Abbott2, Mark K Larson3
1Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA.
由于社会和心理压力因素,心血管疾病不成比例地影响美洲原住民. 解决历史创伤和慢性压力对于改善这些社区心血管健康结果至关重要.
科学领域:
- 公共卫生 公共卫生
- 心血管医学 心血管医学
- 健康差异 在健康上的差异
背景情况:
- 与美国其他种族/种族群体相比,美洲原住民患心血管疾病 (CVD) 的负担不成比例.
- 现有的研究往往忽视了社会和心理因素对美国土著人口中心血管疾病的影响.
- 文化和历史因素加剧可修改的心血管疾病风险因素,如这些社区内的营养不良,不活动,肥胖和物质使用.
研究的目的:
- 研究美国原住民社会/心理压力因素和心血管健康差异之间的复杂联系.
- 突出历史创伤和持续的压力因素在加剧慢性压力的作用.
- 为制定有针对性的策略提供信息,以改善心血管疾病的结果.
主要方法:
- 这项研究综合了有关美国原住民心血管疾病风险因素,患病率和结果的现有研究.
- 它研究了文化,历史和社会经济因素对心血管疾病的影响.
- 分析了慢性压力路径 (下丘脑-垂体-上腺和自主神经系统) 在心血管疾病发展中的作用.
主要成果:
- 社会和心理因素,包括历史创伤和慢性压力,对美国原住民的心血管疾病风险作出了重大贡献.
- 慢性压力反应会增加炎症和心血管功能障碍,从而增加心血管疾病的风险.
- 由于文化/历史因素加剧了可修改的风险因素加剧了这个问题.
结论:
- 了解慢性压力和心血管疾病之间的联系对于解决美洲原住民的健康差异至关重要.
- 有效的策略必须承认并减轻历史创伤和持续压力因素的影响.
- 干预措施应侧重于文化相关的方法,以改善心血管健康结果.
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