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Updated: May 31, 2025

Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models
08:33

Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models

Published on: March 24, 2019

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直接和间接的蛋白质相互作用将FUS聚合与希斯连接到ALS/FTD酵母模型中的翻译后修饰失调和生长抑制

Seth A Bennett1,2, Samantha N Cobos1,3, Raven M A Fisher1,2

  • 1Department of Chemistry and Biochemistry, Brooklyn College, Brooklyn, NY 11210, USA.

Journal of fungi (Basel, Switzerland)
|January 24, 2025
PubMed
概括

像ALS和FTD这样的神经退行性疾病中的FUS蛋白聚合破坏了表观遗传学. 这项研究揭示了FUS是如何导致关键酶的核排斥的,从而导致改变了基因质标记和潜在的治疗点.

关键词:
这就是FUS FUS.这就是Ipl1的意思.没有了,没有了.Rtt1099 在这里生活骨髓缩侧面硬化症 (ALS) 是一种表观遗传学是指表观遗传学.前性痴呆症前性痴呆症基质子翻译后的修改

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