非洲瘤病消除措施的影响:系统审查
Policarpo Ncogo1, Christine Giesen2, María Jesús Perteguer3,4
1Fundación Estatal, Salud, Infancia y Bienestar Social (FCSAI), 28029 Madrid, Spain.
Tropical medicine and infectious disease
|January 24, 2025
概括
大规模分发ivermectin对非洲的胆固醇病控制产生了积极影响,在某些地区中断了传播. 然而,干预措施不足以实现世卫组织2030年消除目标,需要进一步制定打击河盲的战略.
科学领域:
- 公共卫生 公共卫生
- 热带医学 热带医学
- 流行病学 流行病学
背景情况:
- 瘤眼病或河盲是一种被忽视的热带疾病 (NTD),是世卫组织消除的目标.
- 撒哈拉以南非洲地区承担了全球99%以上的瘤病负担.
- 世卫组织的NTD路线图 (2021-2030) 概述了消除疾病的基本措施.
研究的目的:
- 评估在非洲实施的瘤病干预措施的影响.
- 评估在非洲特有国家消除球病的目标方面取得的进展.
主要方法:
- 从2021年11月到2022年4月,根据PRISMA指南进行了系统的文献审查.
- 选择了自1974年以来在非洲对血病控制措施的研究.
- 在PubMed,Scopus,Embase和CENTRAL数据库中进行文献搜索,包括西班牙语,英语,法语,德语和葡萄牙语的文章.
主要成果:
- 来自19个非洲国家的63篇文章符合纳入标准.
- 艾弗梅克丁的大众分发是研究的主要干预措施 (n=51).
- 11个国家至少在一个地区中断了氏球菌病的传播,11个国家没有实现这一目标,1个国家在消除后经历了疾病的复发.
结论:
- 瘤病控制干预措施已经证明有效地对抗这种疾病.
- 目前的干预措施本身不足以实现世卫组织2030年消除的目标.
- 需要采取额外的策略和考虑,以实现对瘤病的提议消除目标.
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