在麦加医院出现登革热的患者中估计和描述登革热血型
Sami Melebari1, Abdul Hafiz2, Hatim A Natto3
1Department of Molecular Biology, The Regional Laboratory, Ministry of Health, Makkah 21955, Saudi Arabia.
Tropical medicine and infectious disease
|January 24, 2025
概括
登革热病毒血清型2在2023年4月至2024年5月期间,在沙特阿拉伯的麦加最为普遍. 持续的登革热血型监测对于疫情预测和减轻严重登革热风险至关重要.
科学领域:
- 医学昆虫学 医学昆虫学
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 登革热是四种登革热病毒 (DENV) 血清型引起的重大公共卫生问题.
- 虽然感染一种血清型会对该特定类型产生终身免疫力,但个体仍然容易感染其他血清型,增加严重登革热的风险.
- 了解循环的血清型对于有效的疾病控制和预防策略至关重要.
研究的目的:
- 调查沙特阿拉伯麦加的四种登革热病毒血清型 (DENV-1,DENV-2,DENV-3和DENV-4) 的流行情况.
- 为了确定患有登革热的患者中最常见的登革热血型.
- 突出需要持续监测登革热血清型在一个高国际旅行的地区.
主要方法:
- 使用麦加地区实验室医疗记录数据进行了横截面研究.
- 从2023年4月至2024年5月期间被诊断患有登革热的患者收集了样本.
- 进行登革热病毒血型鉴定,以确定每个血型的患病率.
主要成果:
- 总共分析了238个登革热阳性样本.
- 登革热病毒2型 (DENV-2) 是最经常检测到的血清型 (患病率最高),其次是DENV-1,DENV-3和DENV-4.
- 少数样本 (11) 呈阳性登革热,但未被确定为四种常见血清型中的任何一种,这表明其他血清型的潜在循环.
结论:
- 根据研究期间,登革热病毒2型是沙特阿拉伯麦加的主要血清型.
- 未确定的登革热阳性样本的存在需要进一步调查新型或不常见的血清型,特别是考虑到麦加作为全球旅游中心的地位.
- 持续监测登革热血型对于早期发现疫情和管理易感人群中严重登革热病例至关重要.
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