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调节由PEGylated信使RNA-脂质纳米粒子疫苗诱导的免疫反应

Hyein Jo1, Jaewhoon Jeoung1, Wonho Kim1

  • 1Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon 24341, Republic of Korea.

Vaccines
|January 24, 2025
PubMed
概括

传递器RNA (mRNA) 疫苗使用脂质纳米粒子 (LNP) 进行输送. 本综述详细介绍了mRNA诱导的先天免疫和疫苗中对聚乙烯糖醇 (PEG) 的不良反应,并探索了更安全的LNP疫苗开发策略.

关键词:
这是ABC现象.这就是PEG PEG PEG.过敏 过敏 过敏补充补充补充补充补充补充补充.免疫耐受性 免疫耐受性这是先天免疫力.在mRNA-LNP中.

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