食物感染和沙门氏菌:当前的初级预防工具和未来的前景
Antonella Zizza1, Alessandra Fallucca2, Marcello Guido3
1Institute of Clinical Physiology, National Research Council, 73100 Lecce, Italy.
Vaccines
|January 24, 2025
概括
非伤寒型沙门氏菌 (NTS) 引起人类重大疾病,受污染的动物食品是主要来源. 由于耐药性和疾病负担的增加,开发有效的疫苗至关重要.
科学领域:
- 微生物学 微生物学
- 公共卫生 公共卫生
- 免疫学 免疫学 免疫学
背景情况:
- * *沙门氏菌*是主要的动物感染和食物传播病原体,引起沙门氏菌病.
- *非伤寒型沙门氏菌 (NTS) 血清病毒如*S.enteritidis*和*S.typhimurium*构成一个重大的全球健康挑战.
- *目前的预防依赖于食品安全实践,但对NTS缺乏人类疫苗.
研究的目的:
- * 审查沙门氏病的流行病学负担.
- *讨论NTS感染的初级预防策略.
- * 探索NTS疫苗的现状和未来前景.
主要方法:
- *关于沙门氏病的流行病学数据的文献综述.
- *分析当前的NTS预防和控制策略.
- * 审查NTS疫苗开发,包括活体减弱,亚单位和重组方法.
主要成果:
- *NTS感染,主要来自受污染的动物食品,导致广泛的胃肠炎和全身性疾病.
- *多药耐药菌株和高疾病成本凸显了迫切需要新的干预措施.
- *NTS的疫苗开发正在进展,受到成功的伤寒疫苗的启发.
结论:
- * NTS仍然是一个关键的公共卫生问题,需要采取新的控制措施.
- *开发有效的NTS疫苗是减少疾病发生率和影响的有希望的途径.
- *对候选疫苗的持续研究对于打击NTS日益增长的威胁至关重要.
相关概念视频
Preventive Healthcare Services
960
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
960
Levels of Health Promotion and Illness Prevention
12.1K
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
In primary prevention, actions taken before disease onset prevent the disease from...
12.1K
Infection
7.6K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.6K
Healthcare Associated Infections II: Preventive Measures
2.4K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.4K
Transmission-based Precautions I: Contact, Enteric, and Droplets
3.3K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
3.3K
Steps in Outbreak Investigation
105
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
105


