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[末期慢性病患者的神经认知表现:保守医学管理与血液透析之间的差异]
Luna Sánchez1, Bárbara Lanis2, Nicolás Meza3
1Escuela de Medicina, Universidad de Valparaíso, Valparaíso, Chile.
Revista medica de Chile
|January 24, 2025
概括
接受血液透析 (HD) 的患者与慢性病 (CKD) 的保守管理患者相比,表现出执行功能受损. 这种认知衰退,特别是在口头抑制控制中,即使在正常的认知查结果中也很明显.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 神经心理学 神经心理学
- 认知科学 认知科学
背景情况:
- 在末期慢性病 (CKD) 患者接受血液透析 (HD) 的认知表现缺乏共识.
- 了解CKD患者的认知进化对于综合护理至关重要.
研究的目的:
- 分析和比较末期CKD患者的认知表现,这些患者接受了保守的治疗,而不是血液透析.
- 为了确定受血液透析治疗影响的特定认知领域.
主要方法:
- 采用了横截面研究设计.
- 认知表现使用INECO正面查 (IFS) 仪器进行评估.
- 分析了12名患者,其中6名在保守管理组,6名在血液透析组.
主要成果:
- 与保守管理组 (21.5±3.96) 相比,血液透析患者在IFS总得分上得分明显较低 (14.4±6.29).
- 在口头抑制控制中观察到显著差异,血液透析组的得分较低 (1.83±1.17) 与保守组 (4±0.89) 相比.
- 没有发现与其他认知测试 (如简称MMSE,ACE-III,TMT-A和B,Grober和Buschke测试,Stroop测试和波士顿测试提名测试) 有意义的关联.
结论:
- 接受血液透析的末期慢性病患者表现出执行功能受损.
- 这种障碍即使在像MMSE这样的标准认知查看起来正常时也很明显.
- 血液透析患者的认知缺陷需要进一步调查和临床考虑.
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