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Updated: May 31, 2025

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在体内,RNase T2抑制TLR13介导的自身炎症

Carlos Gomez-Diaz1, Wilhelm Greulich1, Benedikt Wefers2,3,4,5

  • 1Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.

The Journal of experimental medicine
|January 24, 2025
PubMed
概括

RNase T2 缺乏导致神经炎症,允许异常RNA积累,激活托尔类受体13 (TLR13). 恢复RNase T2功能可以解决这种炎症,识别TLR13作为潜在的自我传感器.

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