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通过MS1-中心的同位素N,N-二甲基氨酸 (iDiLeu) 标签,在人类脑脊液中绝对量化氨酸代谢物

Olga Riusech1, Ling Hao2, Lingjun Li3,4,5,6

  • 1Department of Chemistry, University of Wisconsin, Madison, WI, USA.

Analytical and bioanalytical chemistry
|January 24, 2025
PubMed
概括

这项研究引入了一种使用同位素N,N-二甲基白 (iDiLeu) 标记来量化氨基代谢物的新方法. 这种技术增强了代谢物检测,并且可以在没有昂贵的同位素标记标准的情况下进行准确的量化,这有助于疾病研究.

关键词:
绝对量化的绝对量化.阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.人类大脑脊髓液的人类脑脊髓液这样做是愚蠢的.质谱测量质量谱测量它的代谢物是代谢物.

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