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Updated: May 31, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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氨基酸结合复合体对DNA结构的影响

Deepak Shrestha1, Bett Kimutai1, Christine S Chow2

  • 1Department of Chemistry, Wayne State University, Detroit, MI, USA.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
|January 24, 2025
PubMed
概括

氨基酸结合 (II) 复合物 (AAPt) 作为抗癌药物表现有前途,其中一种AAPt对前列腺癌细胞具有与西斯 (cisPt) 相似的疗效,但毒性降低. 这些AAPt复合体还诱导DNA曲,提供新的治疗途径.

关键词:
与氨基酸结合的 (II) 化合物反扩散活动的反扩散活动.西斯普拉丁 (Cisplatin) 是一种基因曲折是指DNA曲.

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