通过专家小组,防止骨科创伤外科观察研究中的混:系统性审查
Rolf H H Groenwold1,2, L X van Rossenberg3, D P J Smeeing4
1Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, the Netherlands. R.H.H.Groenwold@lumc.nl.
概括
专家小组可以通过选择具有治疗均衡的患者来减少观察性研究中的混,专家不同意. 本系统性审查提供了对这种医学治疗研究方法的见解.
科学领域:
- 整形外科创伤外科手术
- 观察性研究是指观察性研究.
- 临床研究方法论临床研究方法论
背景情况:
- 混是观察性研究的一个重大挑战.
- 专家对最佳治疗的分歧可能表明患者一级的治疗均衡.
- 缓解混对于可靠的治疗效果估计至关重要.
研究的目的:
- 通过专家小组进行患者选择,系统地审查观察性研究.
- 探索专家小组在控制混方面的潜力.
- 为研究中的专家小组的应用提供建议.
主要方法:
- 骨科创伤外科手术文献的系统审查.
- 确定使用专家小组参与患者纳入的研究.
- 分析专家小组用于参与者选择的方法.
主要成果:
- 四项研究使用了基于专家分歧的专家小组.
- 制定了关于报告小组特征,提供的信息,不同意标准,患者选择和统计分析的建议.
- 对专家小组的实际应用获得了洞察力.
结论:
- 专家小组是减轻观察性研究中混的宝贵工具.
- 这种研究设计可以提高医学治疗研究的内部有效性.
- 鼓励进一步讨论和采用专家小组,以提高研究质量.
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