男性的三:男性不孕症的一个被忽视的因素?
Seyed Ali Hosseini1, Mohammad Matini1, Maryam Bahmanzadeh2,3
1Department of Medical Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, P.O. Box: 65157838736, Hamadan, Iran.
Acta parasitologica
|January 24, 2025
概括
通过分子方法在一个不孕不育的男性身上检测到了性传播感染的三虫病. 这表明寄生虫可能会导致男性不育,这需要进一步调查Trichomonas vaginalis的影响.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 生殖医学 生殖医学
背景情况:
- 三病是一种常见的性传播感染,由Trichomonas vaginalis引起.
- 在男性中,它通常是无症状的,导致诊断不足.
- 三病在男性不孕症中的作用尚不清楚.
研究的目的:
- 为了确定在参加生育和不孕中心的男性中三菌病的频率.
- 调查三病与男性不孕不育之间的潜在联系.
- 评估检测男性三虫病的诊断方法.
主要方法:
- 一项涉及197名寻求不孕症治疗的男性志愿者的横截面研究.
- 收集和分析尿液和精液样本.
- 显微镜,培养和分子分析 (PCR和测序) 用于检测T. vaginalis.
主要成果:
- 显微镜和培养未能检测到T. vaginalis.
- 通过PCR和测序,在一个患有严重精子异常的不孕男性中发现了一例T. vaginalis (G基因型) 病例.
- 参与者33岁,精子正常度为0.3%,运动率为19%.
结论:
- 三虫病可能是导致男性不孕症的一个被忽视的因素.
- 分子技术是有效的检测T. vaginalis在男性样本.
- 需要进一步的研究来了解T. vaginalis对男性生殖健康的影响.
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